Tissue and Organ bioengineering

Jean-Charles Duclos-Vallée
Jean-Charles Duclos-Vallée is professor of Hepatology at Paris-Sud university and director of the University Hospital Department Hepatinov at Hospital Paul-Brousse. His main research topics are hepato-virology, hepatocellular carcinoma, metabolic and autoimmune liver disease and transplantation. He belongs to the Agence Nationale de Recherche sur le Sida et les Hépatites Virales and is in charge of the follow-up of several cohorts of patients with severe liver diseases. He has recently engaged in innovative therapies of liver diseases including gene therapy and regenerative medicine. He does his research in the group 2 of Inserm U1193. Jean-Charles Duclos-Vallée is the coordinator of the iLite project (innovations in Liver tissue engineering) aiming to bio-construct a liver for transplantation.

Dominique Franco
Dominique Franco is Emeritus professor of digestive surgery at University Paris-Sud. After a career devoted to liver surgery and treatment of hepatocellular carcinoma, he developed a research program on regenerative therapy of liver diseases and organ bio-construction. He is a member of the group 2 research unit of Inserm U-1193. In 2014, he created CellSpace, an association for the development of tissue and organ bioengineering in France, with the objective of gathering all researchers in this field. He has 280 international publications in the field of liver surgery, hepatocellular carcinoma and regenerative medicine

Marie-Noëlle Labour
Marie-Noëlle is the community manager and currently working as a postdoctoral researcher in the INSERM Unit U1148, Laboratory for Vascular Translational Science, in Paris. She is developing hepatic organoid in a 3D polysaccharide hydrogel for the RHU project iLite, Innovation for Liver Tissue Engineering. Her research interests include biomimetic and bioactive biomaterials for tissue engineering and a more fundamental approach to characterize cellular micro-environments to gain a better understanding of diseases and offer adapted therapeutic strategies. She obtained her PhD in 2012 from the University of Montpellier I on the development of a collagen-based functionalized 3D biomimetic matrix for neural differentiation and the study of amyloïd aggregates toxicity mechanisms. She then joined D. Hoey’s group as a research fellow and lab manager in the University of Limerick and later in Trinity College Dublin. Her studies focused on orthopedics and biomechanics, more specifically aiming at understanding the role of Transforming Growth Factor β1 in the recruitment of human Mesenchymal Stem Cells for bone remodeling and developing a polymer-calcium phosphate composite for bone tissue engineering.