Resistance to antibacterial agents

Closed
Course
en
English
15 h
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Source
  • From www.fun-mooc.fr
Conditions
  • Free Access
  • Free certificate
More info
  • 28 Sequences
  • Introductive Level
  • Starts on January 10, 2021
  • Ends on March 2, 2021

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Course details

Syllabus

Week 1: Antibacterial agents / Semaine 1 : Agents antibactériens
  • Mode of action / Mode d'action
  • Origin and biosynthesis / Origine et biosynthèse
  • Impact on Human Health / Impact sur la santé humaine
  • Antibiotherapy / Antibiothérapie
  • Veterinary use / Utilisation vétérinaire
Week 2: Emergence of resistant bacteria / Semaine 2 : Emergence des bactéries résistantes
  • Resistance Mechanisms / Mécanismes de la résistance
  • Antibacterial resistance in the community and the hospital / Résistance aux antibiotiques dans les hôpitaux
  • Epidemiology of Bacterial Resistance in Europe / Épidémiologie de la résistance bactérienne en Europe
  • Bacterial resistance in low- and middle-income countries countries / Résistance bactérienne dans les pays à revenus faibles et moyens
Week 3: Detection of resistant bacteria / Semaine 3 : Détection des bactéries résistantes
  • Phenotypic approaches / Approches phénotypiques
  • Genotypic approaches / Approches génotypiques
  • In silico antibiogram: Genomic approaches / Antibiogrammes in silico: approches génomiques
  • Automated approaches / Automatisation des procédures
Week 4: Origin of antibiotic resistance and dissemination /Semaine 4 : Origine et dissémination de la résistance aux antibiotiques
  • Natural versus Acquired Resistance / Résistance naturelle et acquise
  • Origin of resistance genes / Origine des gènes de la résistance
  • Role of the environment / Rôle de l'environnement
  • Transferability of resistance genes / Transférabilité des gènes de la résistance
  • Evolution of bacterial populations / Évolution des populations bactériennes
Week 5: Controlling the emergence and spread of bacterial resistance / Semaine 5 : Contrôle de la survenue et de la diffusion de la résistance bactérienne
  • Consumption and Inappropriate use of antibiotics / Consommation et utilisation inappropriée des antibiotiques
  • Antibiotics stewardship / Gestion de l'utilisation des antibiotiques
  • Mastering resistance in hospitals / Contrôle de la résistance en milieu hospitalier
  • Economic cost of ABR / Coût économique de la résistance aux antibiotiques
  • Social consequences of bacterial resistance / Conséquences sociales de la résistance bactérienne
Week 6: New antibiotics and alternatives to antibiotics /Semaine 6 : Nouveaux antibiotiques et traitements alternatifs
  • Revisiting "old" molecules / Nouvelles utilisations de molécules anciennes
  • New targets : from leads to candidate / Les nouvelles cibles
  • Anti-virulence Strategies / Stratégie anti virulence
  • Phagotherapy / Phagothérapie
  • CRISPR tools to study and fight antibiotic resistance / L'utilisation de CRISPR pour étudier et combattre la résistance aux antibiotiques

Prerequisite

This MOOC is aimed at undergraduate, graduate and PhD biology students, medical doctors, teachers, researchers and all those who want to learn how antibacterial agents work and how resistant strains have emerged and disseminated. A good scientific background is recommended to follow this MOOC.

Ce MOOC est destiné aux étudiants de biologie, du premier cycle à la thèse, aux médecins, aux enseignants, aux chercheurs, et plus généralement à tous ceux qui s'intéressent à la résistance aux agents antibactériens et qui veulent comprendre comment ces souches de bactéries résistantes sont apparues et se sont disséminées. Un bon bagage scientifique est recommandé pour suivre ce MOOC (niveau licence).

Instructors

Dr. Béatrice BERÇOT
Head of the Clinical Bacteriology Laboratory of the St Louis Hospital, Paris. Bacteriologist, medical doctor and Member of the Team Infection, Antimicrobials Modelling Evolution (IAME), Paris-Diderot University.

Prof. Didier MAZEL
Head of the "Bacterial Genome Plasticity" Research Unit, Institut Pasteur. Director of the "Genome analysis" Course Institut Pasteur. Chairman of the Department of "Genomes and Genetic", Institut Pasteur.

Prof. Patrick TRIEU-CUOT
Head of the "Biology of Gram-positive pathogens" Research Unit, Institut Pasteur. Director of the "Bacterial Resistance to Antibiotics" Course, Institut Pasteur.

Editor

The Institut Pasteur is a private, not-for-profit French foundation based in Paris, dedicated to the study of biology, micro-organisms, diseases and vaccines.

Created in 1888 thanks to an international public subscription, it is named after Louis Pasteur1, its founder and first director, who in 1885 developed the first vaccine against rabies.

For over a century, the Institut Pasteur has been at the forefront of the fight against infectious diseases. In 1983, this international research organisation was the first to isolate the human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS). Over the years, it has been responsible for revolutionary discoveries that have enabled medicine to control virulent diseases such as diphtheria, tetanus, tuberculosis, poliomyelitis, influenza, yellow fever, epidemic plague, hepatitis B and AIDS.

Platform

France Université Numérique is the broadcaster of the online courses of French higher education institutions and their partners.

It operates several platforms of diffusion, of which the best known, FUN MOOC, is the first French-speaking academic platform worldwide. Thanks to many partner institutions, this platform offers a vast catalog of courses enriched daily with various themes and current events.

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