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Understanding Cancer Metastasis
课程
en
英语
15 时
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课程详情
教学大纲
- Week 1 - History and Overview of Metastasis
In this first module, we'll concentrate on the history and overview of metastasis and give you a flavor of how cancer is defined as well as some of the history surrounding how we began to understand metastasis. - Week 1 - Primary Tumor Growth and Neoangiogenesis
In this module, we'll focus on uncontrolled cell division, which is a defining property of cancer, as well as mutation and neoangiogenesis and their roles in tumor formation. We'll also take a look at a primary tumor microenvironment and its component cell typ... - Week 2 - EMT / Invasion / Intravasation
During this module, we'll turn our attention to the next steps after the initial primary tumor formation, epithelial to mesenchymal transition of cancer cells, and local tumor invasion and intravasation into blood or lymph vessels. - Week 2 - Survival in the Circulation and Extravasation
We'll now take a close look at cancer survival within the circulation, the role of the circulatory system in metastasis, the genetic determinants of metastatic potential, signalling mechanisms, chemokines, the dock and lock hypothesis, and extravasation. - Week 3 - Dormancy and Secondary Tumor Growth
In this module, we'll focus on dormancy and secondary tumor growth and how they contribute to the lethality of cancer. - Week 3 - Morbidity and Mortality Associated with Metastasis
In the previous modules, we've looked closely at the sequential steps of metastasis and some of the biology of how metastasis occurs. Now, we'll turn our attention to morbidity and mortality, or in other words, how cancer hurts and kills people.
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讲师
Kenneth Valkenburg
Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
Jelani Zarif
Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
Haley Axelrod
Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
Sarah Amend
Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
Kenneth J. Pienta, M.D.
The Donald S. Coffey Professor of Urology
The James Buchanan Brady Urological Institute
编辑
约翰霍普金斯大学（JHU）是一所美国私立大学，位于马里兰州巴尔的摩市。它在华盛顿特区、意大利博洛尼亚、新加坡和中国南京也设有校区。约翰-霍普金斯大学的名字源于一位富有的企业家约翰-霍普金斯，他在去世时将 700 万美元遗赠给了这所大学。
约翰霍普金斯大学是美国最负盛名的大学之一（尤其是其医学和公共卫生学院以及国际事务学院），它将自己定义为美国领先的 "研究型大学"。建校之初，它主要受到海德堡大学和威廉-冯-洪堡德国教育模式的启发。2019 年，有 39 位诺贝尔奖获得者的名字与这所大学有关2。
平台
Coursera是一家数字公司，提供由位于加利福尼亚州山景城的计算机教师Andrew Ng和达芙妮科勒斯坦福大学创建的大型开放式在线课程。
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