Molecular Evolution (Bioinformatics IV)

课程
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24 时
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课程详情

教学大纲

  • Week 1 - Week 1: Introduction to Evolutionary Tree Construction

    Welcome to our class!

    In this class, we will consider the following two central biological questions (the computational approaches needed to solve them are shown in parentheses):

    1. Weeks 1-3: Which Animal Gave Us SARS? (Evolution...
    2. Week 2 - Week 2: More Algorithms for Constructing Trees from Distance Matrices

      Welcome to Week 2 of class!

      Last week, we started to see how evolutionary trees can be constructed from distance matrices.  This week, we will encounter additional algorithms for this purpose, including the neighbor-joining algorithm, which has...

    3. Week 3 - Week 3: Constructing Evolutionary Trees from Characters

      Welcome to week 3 of class!

      Over the last two weeks, we have seen several different algorithms for constructing evolutionary trees from distance matrices.

      This week, we will conclude the current chapter by considering what happens if we use ...

    4. Week 4 - Week 4

      Welcome to week 4 of the class!

      Did birds evolve from dinosaurs? Over the next two weeks, we will see how we could analyze molecular evidence in support of this theory. You can find this week's Bioinformatics Cartoon from Randall Christopher at the ...

    5. Week 5 - Week 5: Resolving the T. rex Peptides Mystery?

      Welcome to week 5 of class!

      Last week, we asked whether it is possible for dinosaur peptides to survive locked inside of a fossil for 65 million years. This week, we will see what this question has to do with statistics; in the process, we will see ...

    6. Week 6 - Week 6: Bioinformatics Application Challenge

      Welcome to the sixth and final week of the course!

      In this week's Bioinformatics Application Challenge, we will use reconstruct an evolutionary tree of ebolaviruses and use it to determine the origin of the pathogen that caused the recent outbreak i...

先决条件

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讲师

Pavel Pevzner
Professor
Department of Computer Science and Engineering

Phillip Compeau
Visiting Researcher
Department of Computer Science & Engineering

编辑

加州大学圣地亚哥分校是位于加利福尼亚州圣地亚哥的一所公立赠地研究型大学。加州大学圣地亚哥分校成立于 1960 年,位于斯克里普斯海洋学研究所附近,是加州大学十个校区中最南端的一个,提供 200 多个本科和研究生学位课程,在校本科生 33,096 人,研究生 9,872 人。

加州大学圣地亚哥分校被认为是世界上最好的大学之一。多份出版物将加州大学圣地亚哥分校的生物科学系和计算机科学系评为世界前十名。

平台

Coursera是一家数字公司,提供由位于加利福尼亚州山景城的计算机教师Andrew Ng和达芙妮科勒斯坦福大学创建的大型开放式在线课程。

Coursera与顶尖大学和组织合作,在线提供一些课程,并提供许多科目的课程,包括:物理,工程,人文,医学,生物学,社会科学,数学,商业,计算机科学,数字营销,数据科学 和其他科目。

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