Design and Interpretation of Clinical Trials

课程

英语

12 时

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Week 1 - Types of Trial Designs
This week, we explore different types of trial designs, including parallel, crossover, group allocation, factorial, large simple, equivalency, non-inferiority, and adaptive designs.
Week 2 - Randomization and Masking
This week we discuss two key design features of randomized clinical trials used to protect against bias, randomization and masking.
Week 3 - Outcomes and Analysis
This week focuses on a key design issue - selecting the primary outcome. We will also cover the gold standard for analysis of clinical trials, which is including all the participants in the analysis regardless of their actual treatment.
Week 4 - Ethics
This week focuses on a key issue in the field of clinical trials, the ethics of experimentation in humans.
Week 5 - Reporting Results
This week, we focus on reporting results of clinical trials in publications. We cover the Consolidated Standards of Reporting Trials (CONSORT) guidelines.
Week 6 - Randomized Clinical Trials
This week, we focus on whether RCTs are still the gold standard for evaluating evidence.

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Janet Holbrook, PhD, MPH
Associate Professor, Epidemiology
Bloomberg School of Public Health

Lea T. Drye, PhD
Assistant Scientist, Epidemiology
Bloomberg School of Public Health

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