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Bioelectricity: The Mechanism of Origin of Extracellular Potentials
МООК
en
Английский
7 h
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- Self-paced
- Free Access
- Fee-based Certificate
- 7 Sequences
- Intermediate Level
Course details
Syllabus
- Week 1 - Week 1
A brief history of extracellular measurements, and an example of such a recording. The goal is to understand the amplitudes and time variation of such measurements, as well as learn about some interesting and useful historical events. - Week 2 - Week 2
A presentation of the cylindrical fiber model of a nerve. The goal is to see how this geometrically simple model of a nerve actually is sufficient to explain complex bioelectric events within and around electrically active tissue. One learns that currents a... - Week 3 - Week 3
Notable and useful aspects of extracellular wave forms are their changes in shape. What causes such changes? Two illuminating examples are studied, one that does not, and then another that does. - Week 4 - Week 4
Weeks 1 to 3 present some intriguing concepts and explain them with drawings and sketches. Do the wave forms so drawn have any connection with real tissue? Indeed they do. The goal of this week is to examine some specific experimental wave forms that were me... - Week 5 - Week 5
The concepts of week 3 give insight, but there is power in equations and numbers. The goal of week 5 is to show how the models of week 3 can be represented quantitatively, so that one can go beyond asking “What?” and ask “How much?” With equations available,... - Week 6 - Week 6
This week’s goal is to introduce the concept and the mathematical definition of dipole sources. Such sources pair a current source and current sink, separated in a specific orientation by a small distance. A dipole model allows easy evaluation of many electr... - Week 7 - Week 7
As a conclusion to the course, two diverse subjects are considered. One, the multipole expansion, is used when one has no model of the true origin of observed potentials but still needs to create an “equivalent” model to represent the data. The other, cardia...
Prerequisite
None.
Instructors
Dr. Roger Barr
Anderson-Rupp Professor of Biomedical Engineering and Associate Professor of Pediatrics
Biomedical Engineering, Pediatrics
Editor
L'université Duke est une université de recherche privée nord-américaine, située à Durham (Caroline du Nord). L'université est nommée d'après la dynastie Duke.
Bien que l'université ne fût officiellement fondée qu'en 1924 (ses racines remontent jusqu'en 1838). Fréquemment appelée la « Harvard du Sud », Duke est l'université la plus sélective du Sud des États-Unis.
L'université est membre de l'Association des universités américaines, une association qui, depuis 1900, regroupe les universités de recherches d'élite d'Amérique du Nord.
Platform
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