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Viral Outbreaks and Pandemics : a One Health Approach
Closed
Cours
en
Anglais
28 h
Ce contenu est noté 0 sur 5
- 8 séquences
- Niveau Avancé
- Débute le 12 février 2024
- Clôture le 9 avril 2024
Détails du cours
Déroulé
Chapter 1 : History and definitions
1-1 What are emerging infectious diseases ?: Arnaud Fontanet. (iP)
1-2 Emerging and reemerging viruses: Antoine Gessain. (IP)
1-3 The one health approach of emerging infectious diseases: Stephan Zientara (ENVA)
Chapter 2 : Animal reservoirs and Zoonoses
2-1 Introduction : analyze the main wild-life reservoirs and the mode of transmissions, indirect or direct, of emerging viruses to humans: Sophie Le Poder (ENVA)
2-2 Apes and link to HIV, HTLV, Ebola: Antoine Gessain (IP)
2-3 Human-nonhuman primate contact as a driver of viral emergence: Tamara Gilles-Vernick (IP)
2-4 Bats and link to Ebola, Nipah, Hendra and beta-coronaviruses: Meriadeg Le Gouil (Univ Caen)
2-5 Avian influenza viruses and link to flu pandemics: Jean-Claude Manuguerra. (IP)
2-6 Sylvatic cycles of arboviruses and link to urban transmission: Anne Lavergne. (IP Guyanne)
2-7 Changes in climate, deforestation, and natural disasters : Joacim Rocklöv (Univ Umea – Sweden)
Chapter 3 : Virologic molecular mechanisms of emergence
3-1 The multiple molecular mechanisms that contribute to virus adaptability, virulence, and emergence: Esteban Domingo (Univ Madrid)
3-2 Newly identified viruses at interfaces between reservoirs/vectors/humans: Marc Eloit (IP)
3-3 Molecular determinants of emergence of influenza A viruses : Sylvie van de Werf (UPC)
3-4 Molecular determinants of emergence of human beta-coronaviruses: Sylvie van der Werf (UPC)
3-5 Molecular determinants of adaptation of arboviruses to new Aedes vectors: Anna-Bella Failloux (IP)
Chapter 4 : Environmental and social factors of epidemic spread.
4-1 Increased movement of people, animals, and goods: François Gary & Chloé Le Gall-Ladevèze (Phylum, Colomiers)
4-2 Influence of urban dynamics: Pascal Handschumarer (Univ Strasbourg)
4-3 Expansion of Aedes aegypti and albopictus: Anna-Bella Failloux (IP)
4-4 Role of infections and transfusion in viral epidemics spread: Arnaud Fontanet (IP)
Chapter 5 : Pandemics
5-1 AIDS : Yazdan Yazdanpanah (UPC-ANRS)
5-2 Influenza : Sylvie van der Werf (UPC)
5-3 Ebola : Denis Malvy (Univ Bordeaux)
5-4 Zika : Arnaud Fontanet (IP)
5-5 SARS, MERS & COVID-19 : Arnaud Fontanet (IP)
5-6 Monkeypox : Antoine Gessain (IP)
Chapter 6 : Preparedness
6-1 Global surveillance – animals: Chadia Wannous (WOAH)
6-2 Global surveillance- humans – IHR – GOARN: Sylvie Briand – WHO)
6-3 Global surveillance - vectors: Norbert Becker (Univ Heidelberg)
6-4 Early intervention – CIBU: Jean-Claude Manuguerra (IP)
6-5 Modeling of early epidemic dynamics: Simon Cauchemez (IP)
6-6 Pathogen discovery tools: Nolwenn DHEILLY (IP)
6-7 Developing new vaccines against emerging viruses – CEPI: Brigitte Autran (SU-COVARS)
6-8 Anticipating social behaviours during pandemics: Anna Friedler (EHESP)
6-9 From Science to Politics: Didier Houssin (OMS-APHP International)
Prérequis
This MOOC is intended for biology students, from the undergraduate to the graduate level, doctors, teachers, researchers, and more generally for all those interested in emergent infectious diseases. A good scientific level is recommended to follow this MOOC (Bachelor of Science).
Intervenants
Pierre-Emmanuel Ceccaldi
Director of the MOOC, Pierre-Emmanuel Ceccaldi is Professor at Université Paris Cité and Team Leader in the Epidemiology and Pathophysiology of Oncogenic Viruses Unit, Institut Pasteur. He is the co-director of the Fundamental Virology course at the Institut Pasteur. His work is focused on the interactions of different viruses with host barriers (blood-brain barrier, intestinal barrier…), and neuromuscular system.
Arnaud Fontanet
Director of the MOOC, Arnaud Fontanet is Director of the Epidemiology of Emerging Diseases Unit at the Institut Pasteur and Professor of Health and Development at the CNAM. He has a doctorate in medicine (Université Paris V) and in public health (Harvard University).
Jean-Pierre Vartanian
Director of the MOOC, Jean-Pierre Vartanian is Associate Professor at Institut Pasteur in the Virology Department. He is the co-director of the Fundamental Virology course at the Institut Pasteur. His work is focused on identifying restriction factors involved in viral replication and the role of cellular RNA/DNA editing enzymes with antiviral activity against a range of human pathogens.
Stephan Zientara
Director of the MOOC, Stéphan Zientara was awarded a doctorate in veterinary medicine in 1987 and a university doctorate in 1995, obtaining his HDR in 2001. Stéphan Zientara is Director of the Anses Animal Health Laboratory in Maisons-Alfort (France), Director of the European Union Reference Laboratory for Equine Diseases and Deputy Director of the European Union Reference Laboratory for Foot and Mouth Disease.
Laurie Pinaud
Community manager of the MOOC. Laurie Pinaud holds a PhD in microbiology and an MPH in epidemiology and public health. She took part in 2015 in the response to the Ebola epidemic outbreak in West Africa with the Pasteur Institute task force. Since 2020, she is a clinical research project manager within the Emerging diseases epidemiology unit of the Pasteur Institute, where she coordinates COVID-19 studies.
Éditeur
L'Institut Pasteur est une fondation française privée à but non lucratif, sise à Paris, qui se consacre à l'étude de la biologie, des micro-organismes, des maladies et des vaccins.
Créé en 1888 grâce à une souscription publique internationale, il est ainsi nommé d'après Louis Pasteur1, son fondateur et premier directeur qui, en 1885, a mis au point le premier vaccin contre la rage.
Depuis plus d’un siècle, l’Institut Pasteur est à la pointe de la lutte contre les maladies infectieuses. Cette organisation internationale de recherche a été la première à isoler en 1983 le virus de l'immunodéficience humaine (VIH), virus qui provoque le syndrome d'immunodéficience acquise (SIDA). Au fil des années, il a été à l'origine de découvertes révolutionnaires qui ont permis à la médecine de contrôler des maladies virulentes, telles que la diphtérie, le tétanos, la tuberculose, la poliomyélite, la grippe, la fièvre jaune, la peste épidémique, l'hépatite B, le SIDA.
Plateforme
France Université Numérique est le diffuseur des cours en ligne des établissements d’enseignement supérieur français et de leurs partenaires.
Il opère plusieurs plateformes de diffusion, dont la plus connue, FUN MOOC, est la première plateforme académique francophone mondiale. Grâce à de nombreux établissements partenaires, cette plateforme propose un vaste catalogue de cours s’enrichissant de jour en jour avec des thématiques variées et d’actualité.
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