Welcome to our class! We are glad that you decided to join us.
In this class, we will consider the following two central biological questions (the computational approaches needed to solve them are shown in parentheses):
Welcome to week 2 of the class!
This week, we will introduce a paradigm called the Burrows-Wheeler transform; after seeing how it can be used in string compression, we will demonstrate that it is also the foundation of modern read-mapping algorithms...
Welcome to week 3 of class!
Last week, we saw how the Burrows-Wheeler transform could be applied to multiple pattern matching. This week, we will speed up our algorithm and generalize it to the case that patterns have errors, which models the biolo...
Welcome to week 4 of class!
This week, we will start examining the case of aligning sequences with many mutations -- such as related genes from different HIV strains -- and see that our problem formulation for sequence alignment is not adequate for ...
Welcome to week 5 of class!
Last week, we introduced hidden Markov models. This week, we will see how hidden Markov models can be applied to sequence alignment with a profile HMM. We will then consider some advanced topics in this area, which are ...
Welcome to the sixth and final week of class!
This week brings our Application Challenge, in which we apply the HMM sequence alignment algorithms that we have developed.
Coursera est une entreprise numérique proposant des formation en ligne ouverte à tous fondée par les professeurs d'informatique Andrew Ng et Daphne Koller de l'université Stanford, située à Mountain View, Californie.
Ce qui la différencie le plus des autres plateformes MOOC, c'est qu'elle travaille qu'avec les meilleures universités et organisations mondiales et diffuse leurs contenus sur le web.