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Demystifying Biomedical Big Data: A User’s Guide
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- 8 séquences
- Niveau Intermédiaire
Détails du cours
Déroulé
Week 1: Introduction and Overview of Bioinformatics Platforms and Resources
- Introduction to the Course -Interview with Bioinformatics at Georgetown University Medical Center. Dr. Robert Clarke, Dean for Research, at Georgetown University Medical Center
- Biomedical Informatics: Enabling Research and Health Care. Interview with Dr. Subha Madhavan, Director of the Innovation Center for Biomedical Informatics (ICBI) at Georgetown University
- Biomedical Big Data: Enabling Personalized Medicine. Interview with Dr. John Marshall, Chief, Hematology and Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center internationally recognized medical oncologist
Week 2: Translational Research and Big Data
- Translational Research
- Translational Research Lecture, Part 1 Part I
- Translational Research Lecture, Part 2 Part II
- The Cancer Genome Atlas
- The Cancer Genome Atlas Lecture
- The Cancer Genome Atlas Demo
- The Cancer Genome Atlas Exercise
- Introduction to G-DOC
- G-DOC Lecture
- G-DOC Demo
- G-DOC Exercise
Week 3: DNA and Big Data
- DNA Copy Number
- DNA Copy Number Lecture
- DNA Copy Number Demo
- DNA Copy Number Exercise
- Genome Sequencing
- Genome Sequencing Lecture, Part 1
- Genome Sequencing Lecture, Part 2
- Genome Sequencing Demo
- Genome Sequencing Exercise
Week 4: RNA and Big Data
- Gene Expression
- Gene Expression Lecture
- Gene Expression Demo
- Gene Expression Exercise
- MicroRNA
- MicroRNA Lecture
- MicroRNA Demo
- MicroRNA Exercise
Week 5: Proteins and Big Data Part I
- Proteomics
- Protein Sequences Lecture
- Protein Interactions Lecture
- Mass Spec Proteomics, Lecture
- Proteomics Exercise
Week 6: Proteins and Big Data Part II
- Proteomics (Continued)
- Data Sharing, Metadata, Data Formats
- Ontologies
- Proteomics Demo, Part 1
- Proteomics Demo, Part 2
- Proteomics Demo, Part 3
- Proteomics Exercise
Week 7: Systems Biology and Big Data
- Systems Biology
- Systems Biology Lecture, Part 1
- Systems Biology Lecture, Part 2
- Systems Biology and Data Analysis Demo
- Systems Biology Exercise
Week 8: Perspectives from the Field and Course Conclusion
- Perspectives from the Field
- Regulatory issues Issues related Related to biomedical Biomedical big Big dataData. Sheila Zimmet, JD, Senior Associate Vice President for Regulatory Affairs, and Ashley Carver, JD, Deputy Conflicts Officer and Regulatory Affairs Associate, Georgetown University Medical Center.
- Enabling Everyone to Share and Use Public Datasets. Interview with Dr. Ben Busby, genomics Genomics outreach Outreach coordinator Coordinator at the National Center for Biotechnology Information (NCBI)
- Interview withCancer Moonshot. Dr. Jerry Lee, Deputy Director, Center for Strategic Scientific Initiatives, Office of the Director, National Cancer Institute, National Institutes of Health
Prérequis
- Background in biology is suggested (high school or undergraduate level). Review of relevant courses in biology and life sciences (e.g. genetics, genomics, DNA/RNA/Protein structure and function, transcription, and translation) is recommended, but not required.
- Courses to explore include (GeorgetownX), (RiceX), (RiceX), and (RiceX).
Intervenants
Bassem R. Haddad
Course Director
Georgetown University Medical Center
Sheila Cohen Zimmet
Senior Associate Vice President for Regulatory Affairs, GU Medical Center
Georgetown University
Robert Clarke
Dean for Research and Professor of Oncology
Georgetown University Medical Center
Yuriy Gusev
Course Director
Georgetown University Medical Center
Peter McGarvey
Course Director
Georgetown University Medical Center
John. L. Marshall
Chief, Hematology and Oncology, Lombardi Comprehensive Cancer Center
Georgetown University Medical Center
Krithika Bhuvaneshwar
Research Associate II (Bioinformatics) and Project Manager, Innovation Center for Biomedical Informatics (ICBI)
Georgetown University
Ben Busby
Genomics Outreach Coordinator at the National Center for Biotechnology Information (NCBI)
Ashlea Carver
Deputy Conflicts Officer and Regulatory Affairs Associate
Georgetown University Medical Center
Jerry SH Lee
Deputy Director, Center for Strategic Scientific Initiatives, Office of the Director, National Cancer Institute, National Institutes of Health, Department of Health and Human Services
Subha Madhavan
Director, Innovation Center for Biomedical Informatics (ICBI)
Georgetown University
Éditeur
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EdX a été fondée par le Massachusetts Institute of Technology et par l'université Harvard en mai 2012. En 2014, environ 50 écoles, associations et organisations internationales offrent ou projettent d'offrir des cours sur EdX. En juillet 2014, elle avait plus de 2,5 millions d'utilisateurs suivant plus de 200 cours en ligne.
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