list 12 sequences
assignment Level : Introductive
chat_bubble_outline Language : English
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Key information

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timer 36 hours in total

About the content

Introductory virology course that covers the interplay between viruses and their host organisms, with with the goal of understanding viral diseases and their prevention.

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Syllabus

Week 1
Infection basics
Entry into the host
Viral spread
Tissue invasion and tropism
Transmission and seasonality
Week 2
Innate immune responses
Interferon
Sentinels and complement
Inflammation
Adaptive immunity
Week 3
Viral virulence
Mechanisms of cell injury I
Mechanisms of cell injury II
Host susceptibility
Week 4
Acute infections
Influenza
Poliomyelitis
Measles
Gastroenteritis
West Nile fever
Week 5
Persistent infections
Persistence by modulating the adaptive response
Two persistent infections
Herpes simplex virus
Epstein-Barr virus
Week 6
Transformation
RNA tumor viruses
Transforming retroviruses
DNA tumor viruses
Epiphenomena of a unique life style
Week 7
Vaccines
How do you make a vaccine?
Inactivated vaccines
Attenuated vaccines
Week 8
Antivirals
Antiviral discovery
Antiviral resistance
Other antiviral targets
HIV antivirals
Week 9
Viral evolution
Drivers of evolution
Error threshold and bottlenecks
Selection
Origins of viruses
Week 10
Emerging viruses
Host-virus interactions
Examples of emerging viruses
SARS and MERS
Canine parvovirus
Week 11
Viroids
Satellites
Transmissible spongiform encephalopathies
Prions
Week 12
HIV and AIDS
The origin of HIV
HIV pathogenesis
An amazing but deadly virus
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Instructors

  • Vincent Racaniello
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Content designer

Columbia University
For more than 250 years, Columbia has been a leader in higher education in the nation and around the world. At the core of our wide range of academic inquiry is the commitment to attract and engage the best minds in pursuit of greater human understanding, pioneering new discoveries and service to society.
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Platform

Coursera

Coursera is a digital company offering massive open online course founded by computer teachers Andrew Ng and Daphne Koller Stanford University, located in Mountain View, California. 

Coursera works with top universities and organizations to make some of their courses available online, and offers courses in many subjects, including: physics, engineering, humanities, medicine, biology, social sciences, mathematics, business, computer science, digital marketing, data science, and other subjects.

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