- From www.coursera.org
How Viruses Cause Disease
Course
en
English
36 h
This content is rated 4.5 out of 5
- Self-paced
- Free Access
- Free certificate
- 12 Sequences
- Introductive Level
Course details
Syllabus
Week 1
Infection basics
Entry into the host
Viral spread
Tissue invasion and tropism
Transmission and seasonality
Infection basics
Entry into the host
Viral spread
Tissue invasion and tropism
Transmission and seasonality
Week 2
Innate immune responses
Interferon
Sentinels and complement
Inflammation
Adaptive immunity
Innate immune responses
Interferon
Sentinels and complement
Inflammation
Adaptive immunity
Week 3
Viral virulence
Mechanisms of cell injury I
Mechanisms of cell injury II
Host susceptibility
Viral virulence
Mechanisms of cell injury I
Mechanisms of cell injury II
Host susceptibility
Week 4
Acute infections
Influenza
Poliomyelitis
Measles
Gastroenteritis
West Nile fever
Acute infections
Influenza
Poliomyelitis
Measles
Gastroenteritis
West Nile fever
Week 5
Persistent infections
Persistence by modulating the adaptive response
Two persistent infections
Herpes simplex virus
Epstein-Barr virus
Persistent infections
Persistence by modulating the adaptive response
Two persistent infections
Herpes simplex virus
Epstein-Barr virus
Week 6
Transformation
RNA tumor viruses
Transforming retroviruses
DNA tumor viruses
Epiphenomena of a unique life style
Transformation
RNA tumor viruses
Transforming retroviruses
DNA tumor viruses
Epiphenomena of a unique life style
Week 7
Vaccines
How do you make a vaccine?
Inactivated vaccines
Attenuated vaccines
Vaccines
How do you make a vaccine?
Inactivated vaccines
Attenuated vaccines
Week 8
Antivirals
Antiviral discovery
Antiviral resistance
Other antiviral targets
HIV antivirals
Antivirals
Antiviral discovery
Antiviral resistance
Other antiviral targets
HIV antivirals
Week 9
Viral evolution
Drivers of evolution
Error threshold and bottlenecks
Selection
Origins of viruses
Viral evolution
Drivers of evolution
Error threshold and bottlenecks
Selection
Origins of viruses
Week 10
Emerging viruses
Host-virus interactions
Examples of emerging viruses
SARS and MERS
Canine parvovirus
Emerging viruses
Host-virus interactions
Examples of emerging viruses
SARS and MERS
Canine parvovirus
Week 11
Viroids
Satellites
Transmissible spongiform encephalopathies
Prions
Viroids
Satellites
Transmissible spongiform encephalopathies
Prions
Week 12
HIV and AIDS
The origin of HIV
HIV pathogenesis
An amazing but deadly virus
HIV and AIDS
The origin of HIV
HIV pathogenesis
An amazing but deadly virus
Prerequisite
None.
Instructors
- Vincent Racaniello
Editor
Columbia University is a private university located in Morningside Heights, in the north-western part of the borough of Manhattan, in New York (United States). Its origins lie in King's College, founded in 1754 by King George II of Great Britain. It is one of the oldest institutions of higher learning in the United States and is part of the Ivy League group of eight of the country's oldest, most famous, most prestigious and most elitist universities.
Columbia is one of the most selective and prestigious universities in the world. The admission rate was 5.1% in 2019, comparable to Harvard and Stanford. Ranked first in the United States for research, it is sixth in the world (fourth in the United States) in the CUWR ranking of the world's top 1,000 universities and eighth in the Shanghai University Rankings.
Platform
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