Key Information
About the content
Step into the world of Tissue Engineering, a rapidly expanding field of applied biology aiming to create artificial organs for transplantation, basic research, or drug development.
Syllabus
Week One: Introduction. definitions, basic principles, structure-function relationships
Week Two: Biomaterials. metals, ceramics, polymers (synthetic and natural). Biodegradable materials, native matrix
Week Three: Tissue culture basics: primary cells vs. cell lines, sterile techniques, plastics, enzymes, reactors and cryopreservation
Week Four: Oxygen transport. diffusion, Michalies-Menten kinetics, oxygen uptake rates, limits of diffusion
Week Five: Principals of self assembly. cell migration, 3D organization and angiogenesis
Week Six: Skin tissue engineering. introduction, scar vs. regeneration, split skin graft, apligraf
Week Seven: Cardiovascular tissue engineering. introduction, blood vessels structure, vascular grafts
Week Eight: Liver tissue engineering. bioartificial liver (BAL) assist device, shear forces , oxygen transport, plasma effects
Week Nine: Liver tissue engineering. self-assembled organoids, decelluarized whole livers
Week Ten: Stem cells. basic principles, embryonic stem cells, induced pluripotent stem cells
Instructors
- Yaakov Nahmias - Center of Bioengineering
Content Designer
Platform
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