- From www.fun-mooc.fr
Malaria
- Free Access
- Free certificate
- 30 Sequences
- Introductive Level
- Starts on October 18, 2020
- Ends on December 6, 2020
Course details
Syllabus
Week 1: History, Epidemiology and clinical presentation of malaria / Historique, épidémiologie et présentation clinique du paludisme
- 1. History of malaria and malaria control / Histoire et contrôle du paludisme
- 2. Epidemiology of malaria / Épidémiologie du paludisme
- 3. Clinical presentation of malaria / Présentation clinique du paludisme
- 4. Pathophysiology of malaria / Physiopathologie du paludisme
- 5. Malaria diagnosis / Diagnostic du paludisme
- 6. Pre-erythrocytic phase (and zoite motility)/ Phase pré-érythrocytaire (et mobilité du zoïte)
- 7. Erythrocytic phase (and zoite invasion) / Phase érythrocytaire et invasion du zoïte
- 8. Sexual and mosquito phase / Phase sexuée du parasite dans le moustique
- 9. Cytoadherence and antigenic Variation / Cytoadhésion et variations antigéniques
- 10. Malaria in Pregnancy / Paludisme pendant la grossesse
- 11. The Plasmodium genome and its expression / Le génome du plasmodium et son expression
- 12. Genomic techniques / Techniques de génomique
- 13. Parasite transfection / Transfection du parasite
- 14. Genome manipulation / Manipulation du génome
- 15. CRISPR-Cas9 / CRISPR-Cas9
- 16. Immunity to Plasmodium/Immunité contre le plasmodium
- 17. Immune evasion/ Échappement immunitaire
- 18. Pre-erythrocytic stage vaccines / Les vaccins de l’étape pré-érythrocytaire
- 19. Blood stage vaccines / Les vaccins de l’étape sanguine
- 20. Transmission blocking vaccines / Les vaccins bloquant la transmission
- 21. Anti-malarial drugs / Les médicaments antipaludéens
- 22. Drug treatment and follow-up/ Traitement antipaludéen et suivi
- 23. Drug treatment and public health / Traitement antipaludéen et santé publique
- 24. Drug resistance / Résistance au traitement
- 25. Parasite metabolism and new drug targets / Métabolisme du parasite et nouvelles cibles thérapeutiques
- 26. Ecology of anopheline mosquitoes / Écologie du moustique anophèle
- 27. Vector control for malaria / Le contrôle des vecteurs du paludisme
- 28. Parasite dormancy and quiescence / Dormance et quiescence du parasite
- 29. The case of Plasmodium vivax / Le cas de Plasmodium vivax
- 30. Malaria elimination / Élimination du paludisme
Prerequisite
This MOOC is aimed at people interested in malaria and in understanding the complex biology of malaria parasites, how they cause the disease and how one can try to develop new tools including drugs and vaccines to combat it.
Ce MOOC s’adresse aux personnes intéressées par le paludisme et souhaitant mieux comprendre la biologie complexe des parasites du paludisme, comment ils provoquent la maladie et comment on peut essayer de développer de nouveaux outils, y compris des médicaments et des vaccins pour la combattre.
We recommend a good scientific background (such as a bachelor of life science).
Un bon niveau scientifique est recommandé pour suivre ce MOOC (licence en Sciences de la Vie).
Instructors
Chetan Chitnis
Chetan CHITNIS received his Ph.D. in Biophysics from the University of California, Berkeley in 1990 and conducted post-doctoral research on malaria at the National Institutes of Health, Bethesda from 1990 to 1995. He returned to India in 1995 to work at the International Centre for Genetic Engineering and Biotechnology (ICGEB) where he established a highly successful group working on basic and translational research on malaria. In 2014, he joined the Institut Pasteur, Paris as Professor in the Department of Parasites and Insect Vectors where he currently heads the Malaria Parasite Biology and Vaccines Unit. His research unit studies the molecular mechanisms that enable malaria parasites to invade host erythrocytes and uses this information to develop vaccines and identify novel drug targets.
Editor
The Institut Pasteur is a private, not-for-profit French foundation based in Paris, dedicated to the study of biology, micro-organisms, diseases and vaccines.
Created in 1888 thanks to an international public subscription, it is named after Louis Pasteur1, its founder and first director, who in 1885 developed the first vaccine against rabies.
For over a century, the Institut Pasteur has been at the forefront of the fight against infectious diseases. In 1983, this international research organisation was the first to isolate the human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS). Over the years, it has been responsible for revolutionary discoveries that have enabled medicine to control virulent diseases such as diphtheria, tetanus, tuberculosis, poliomyelitis, influenza, yellow fever, epidemic plague, hepatitis B and AIDS.
Platform
France Université Numérique is the broadcaster of the online courses of French higher education institutions and their partners.
It operates several platforms of diffusion, of which the best known, FUN MOOC, is the first French-speaking academic platform worldwide. Thanks to many partner institutions, this platform offers a vast catalog of courses enriched daily with various themes and current events.
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