Introduction to the Biology of Cancer
link Source: www.coursera.org
list 6 sequences
assignment Level : Introductive
chat_bubble_outline Language : English
language Subtitles : Catalan, Hebrew
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Key Information

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verified_user Fee-based Certificate
timer 6 hours in total

About the content

Over 500,000 people in the United States and over 8 million people worldwide are dying every year from cancer. As people live longer, the incidence of cancer is rising worldwide and the disease is expected to strike over 20 million people annually by 2030. This open course is designed for people who would like to develop an understanding of cancer and how it is prevented, diagnosed, and treated. The course introduces the molecular biology of cancer (oncogenes and tumor suppressor genes) as well as the biologic hallmarks of cancer. The course also describes the risk factors for the major cancers worldwide, including lung cancer, breast cancer, colon cancer, prostate cancer, liver cancer, and stomach cancer. We explain how cancer is staged, the major ways cancer is found by imaging, and how the major cancers are treated. In addition to the core materials, this course includes two Honors lessons devoted to cancers of the liver and prostate. Upon successful completion of this course, you will be able to: - Identify the major types of cancer worldwide. (Lecture 1) - Describe how genes contribute to the risk and growth of cancer. (Lecture 2) - List and describe the ten cellular hallmarks of cancer. (Lecture 3) - Define metastasis, and identify the major steps in the metastatic process. (Lecture 4) - Describe the role of imaging in the screening, diagnosis, staging, and treatments of cancer. (Lecture 5) - Explain how cancer is treated. (Lecture 6) We hope that this course gives you a basic understanding of cancer biology and treatment. The course is not designed for patients seeking treatment guidance – but it can help you understand how cancer develops and provides a framework for understanding cancer diagnosis and treatment.

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Syllabus

  • Week 1 - Incidence and Etiology of Cancer
    In this first week, we'll get a high-level introduction to the basics of cancer biology as well as incidence and common types of cancer.
  • Week 2 - Genetics of Cancer
    Now, we'll turn our attention to the genetics of cancer, variation and mutation, two-hit hypothesis, and genomic instability.
  • Week 3 - Ten Cellular Hallmarks of Cancer
    All cancers share ten cellular hallmarks. This week, you'll learn to identify these hallmarks in order to distinguish a normal cell from a cancerous cell.
  • Week 4 - Metastasis: The Real Killer
    The lethal agent of cancer is metastasis. This week, we'll take a good look at this deadly event, TNM staging, the metastatic process, and an ecological paradigm.
  • Week 5 - Imaging in Oncology
    This week, we'll examine imaging as a tool for diagnosis, staging, and treatment of cancer.
  • Week 6 - Treatment
    In this final week, we'll examine the variety of treatment options available to doctors and patients as well as the features of clinical trials and how they are used to improve the treatment arsenal.
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Instructors

Kenneth J. Pienta, M.D.
The Donald S. Coffey Professor of Urology
The James Buchanan Brady Urological Institute

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Content Designer

Johns Hopkins University
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
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Platform

Coursera

Coursera is a digital company offering massive open online course founded by computer teachers Andrew Ng and Daphne Koller Stanford University, located in Mountain View, California. 

Coursera works with top universities and organizations to make some of their courses available online, and offers courses in many subjects, including: physics, engineering, humanities, medicine, biology, social sciences, mathematics, business, computer science, digital marketing, data science, and other subjects.

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There are many courses that raise your opinion of an institution. This is to be expected; think about why a university might offer an online class for free. But to my surprise, my opinion of Johns Hopkins went down - way down - as a result of completing this course. Why? "Experts" who couldn't pronounce words ("genome", "radionuclide") used in their own area of expertise. Factually incorrect information, like "both copies of a gene must have a mutation for cancer to occur", which is not true for many genes. Also, a strong tendency to use words, abbreviations, and acronyms that have never been defined, which is not appropriate for an "introduction" to something. I'm not saying there wasn't any good information - there was some - but overall, this class was disappointing.

Published on June 27, 2021
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June 27, 2021
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There are many courses that raise your opinion of an institution. This is to be expected; think about why a university might offer an online class for free. But to my surprise, my opinion of Johns Hopkins went down - way down - as a result of completing this course. Why? "Experts" who couldn't pronounce words ("genome", "radionuclide") used in their own area of expertise. Factually incorrect information, like "both copies of a gene must have a mutation for cancer to occur", which is not true for many genes. Also, a strong tendency to use words, abbreviations, and acronyms that have never been defined, which is not appropriate for an "introduction" to something. I'm not saying there wasn't any good information - there was some - but overall, this class was disappointing.