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Introduction to Stewart’s Model of Physiological Acid-Base Chemistry.
Course
en
English
15 h
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- Self-paced
- Free Access
- Fee-based Certificate
- 5 Sequences
- Introductive Level
Course details
Syllabus
Week 1: Introduction to Stewart's model; Basics of aqueous solutions; The physiology of acid-base balance in medicine; Clinical conundrums in acid-base balance; and The basics of simultaneous equations.
Week 2: Acid-base behaviour of pure water including temperature effects on dissociation coefficient; Acid-base behaviour pure water and a salt with a brief introduction to the concept of SID; Acid-base behaviour of water, salt and a weak acid (protein); Acid-base behaviour of water, salt, weak acid and carbon dioxide; Bicarbonate and respiratory effects; and Solutions containing gases and Henry's law i.e. measurement of gas concentrations in terms of partial pressures.
Week 3: Putting it all together: Summary of the key concepts in acid-base chemistry including the nature of dependant and independent variables; Review of the overall system of acid-base balance in terms of Stewart's model; and Examples from pathology and clinical medicine.
Prerequisite
None.
Instructors
David Rubin
Adjunct Professor, Biomedical Engineering
Wits University
Johan van Schalkwyk
Dr
Wits University
Editor
The University of the Witwatersrand is a South African academic institution located in Johannesburg, Gauteng Province, in the historic Witwatersrand region. The university is nicknamed "Wits". It is the largest and most prestigious university in South Africa.
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