Evolutionary Medicine: Microbes, Medicine, and Humanity's Quest for Survival
date_range Starts on July 1, 2020
event_note End date August 2, 2020
list 4 sequences
assignment Level : Introductive
chat_bubble_outline Language : English
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Key Information

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verified_user Fee-based Certificate
timer 16 hours in total

About the content

Have you ever wondered why we often develop a fever when we get sick? Or a cough? Why do we get cancer? Or the flu? Or allergies? Why do our bodies succumb to disease at all? In this class, we’ll answer these questions by taking a step back in time to consider how our evolutionary past has shaped our health in the present.

Evolutionary medicine integrates an evolutionary biology and anthropology lens with current medical knowledge to enhance our understanding of human health. This class uses topics such as development and aging, human migration, mortality, diseases (infectious, metabolic, and autoimmune), and physiological and behavioral mechanisms of immunity to explore the broad arena of human health within a deep time and global context.

Using this perspective, we will investigate how human populations have co-evolved with microbes for millennia, how our changing environments intersect with our genes to shape phenotypes, how culture and other social factors may influence disease risk, and how to address current emerging health challenges across the globe.

Skills-based course answers :

Taught by faculty in the fields of anthropology, biology, and medicine, this course will prepare students to use evolutionary medicine as a foundation for approaching problems within professional arenas such as medicine, public health, and global health policymaking. Additionally, students can use this course as a skill bridge to other classes related to the applied health sciences.

In this course you will learn:

  • An applied understanding of evolutionary principles to human health
  • Basics about the immune system
  • Human population variation
  • How changing environments influence virulence and disease transmission
  • Biocultural influences on human health

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Syllabus

Week 1: Why do we get sick?

An introduction to sickness behaviors and the immune system through an examination of subject-specific examples such as smallpox, tuberculosis, influenza, and other infectious diseases.

Week 2: Why does selection leave our bodies vulnerable?

The basics of evolutionary theory in the context of how humans have evolved defenses against disease. We consider how our species evolved in environments quite different from our modern world, and how this results in mismatches and tradeoffs in our health.

Week 3: What can our evolutionary past tell us about our health in the present?

An introduction to co-evolution between humans and pathogens, and the factors that affect pathogen virulence and transmission. We’ll examine the “Old Friends” Hypothesis, vaccination, and the emergence of autoimmune and metabolic diseases.

Week 4: How can evolutionary medicine be used to tackle emerging and future health crises?

We’ll examine emerging and waning health threats such as measles, Ebola, and zika in a global and public health context while also considering changing environments and the impact on pathogenicity. In addition, we explore the applications of an evolutionary medicine perspective to global health policymaking.

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Instructors

Randolph Nesse, MD
Co-Founder of the field of Evolutionary Medicine and Foundation Professor
School of Life Sciences, Arizona State University

Katie Hinde, PhD
Associate Professor
School of Human Evolution & Social Change, Arizona State University

Silvie Huijben, PhD
Assistant Professor
School of Life Sciences, Arizona State University

Noah Snyder-Mackler, PhD
Assistant Professor
School of Life Sciences, Arizona State University

Benjamin Trumble, PhD
Assistant Professor
School of Life Sciences, Arizona State University

Melissa Wilson, PhD
Assistant Professor
School of Life Sciences, Arizona State University

Hallie M. Edmonds, PhD
Postdoctoral Research Scholar
Center for Evolution and Medicine, Arizona State University

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