list 7 sequences
assignment Level : Introductive
chat_bubble_outline Language : English
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Key information

credit_card Free access
verified_user Fee-based Certificate
timer 21 hours in total

About the content

Please note: This course was developed in 2014. This course is not actively moderated by course instructors, please use the course forums to collaborate with other learners. Knowledge linking genomics to health and disease is rapidly expanding. Translation of this knowledge into clinical and public health practice offers promising opportunities but also raises a host of ethical, legal, social, and policy questions. Using case examples, this inter-disciplinary course will explore the challenges of genomic and precision medicine. This seven week, inter-disciplinary course provides an introduction to ethical, legal, social, and policy issues that arise in the translation of genomic knowledge into medical and public health practice. It considers challenges in health related and reproductive testing/screening focusing on six specific areas: • Pre‐conception genetic diagnosis, and prenatal testing/screening • Newborn screening • Use of genomic sequencing technologies to diagnose and predict disease • Targeting genomic testing/screening by race/ethnicity • Direct‐to‐consumer genomic testing/screening • Use of “big data” for genomic research and genomic translation Course Objectives 1. Critique the promise of genomics and precision medicine for improving health outcomes for individuals and populations. 2. Through analysis of key cases, demonstrate an understanding of the ethical, legal, social, and policy (ELSI) challenges that accompany the translation of new genomic knowledge into clinical medicine and public health practice. 3. Apply a critical analysis of ELSI concerns to your professional practice (if relevant), your interest as a potential user of genomic knowledge, and as a citizen with a responsibility to shape health policy.

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Syllabus

Week 1: Introduction
Week 2: Reproductive Genetics
Week 3: Screening
Week 4: Genetic Technology in the Prediction and Diagnosis of Disease
Week 5: Race and Genetics
Week 6: Direct-to-Consumer Testing
Week 7: Where Do We Go From Here?
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Instructors

Wylie Burke, MD, PhD
Professor, Department of Bioethics and Humanities, University of Washington
2013-14 Presidential Chair, University of California, San Francisco

Barbara A. Koenig, PhD
Professor of Medical Anthropology & Bioethics
Dept. of Social & Behavioral Sciences, Institute for Health & Aging, & Dept. of Anthropology, History, and Social Medicine

Julie N. Harris-Wai, Ph.D., MPH
Assistant Adjunct Professor
Department of Behavioral and Social Sciences

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Content designer

University of California, San Francisco

The University of California, San Francisco, is dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. UC San Francisco is the only campus in the University of California system dedicated exclusively to the health sciences. UCSF's innovative, collaborative approaches for health care, research and education span disciplines across the health sciences and make it a world leader in scientific discovery and its translation into improved health.

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Platform

Coursera

Coursera is a digital company offering massive open online course founded by computer teachers Andrew Ng and Daphne Koller Stanford University, located in Mountain View, California. 

Coursera works with top universities and organizations to make some of their courses available online, and offers courses in many subjects, including: physics, engineering, humanities, medicine, biology, social sciences, mathematics, business, computer science, digital marketing, data science, and other subjects.

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