Epidemics I

Course

English

Subtitles available

10 h

Source

From www.edx.org

Conditions

Self-paced
Free Access
Fee-based Certificate

More info

5 Sequences
Introductive Level
Subtitles in Chinese

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Course details

Syllabus

Week 1: Epidemics: Past, Present and Future

What is epidemic?
How epidemics of infectious disease arise from historic transitions?
Why novel emerging infectious diseases continue to arise?
Emerging infectious disease, re-emerging infectious disease and zoonosis
Factors leading to infectious disease emergence and re-emergence (microbial factors, climate and weather, changes in ecosystem and land use, human demographics, migrations and behaviour, international travel and commerce, technology, industry and intensive animal husbandry, breakdown in public health due to poverty, wars, natural disasters, and bioterrorism)
Regions with higher risk of future emerging infectious disease and estimated economic costs of emerging infectious disease

Week 2: Discussion on Ebola and Zika Outbreak, and Supplementary Module on Next Generation Informatics for Global Health

How to prepare for the next epidemic?
How to allocate our resources among our fights against different pathogens?
How should we channel our resources?
Vaccines
Antimicrobial resistance
Supplementary module: towards digital pathogen surveillance: a very bumpy, winding road

Week 3: Ecology, Evolution and Emergence of Infectious Diseases

Ecology of infectious diseases
Emerging infectious diseases at the human-animal interface
What is phylogenetic tree?
How to use phylogenetic trees to study an epidemic of infectious disease?
Emergence of highly pathogenic H5N1 Avian Influenza virus in Asia
Emergence of the H7N9 Influenza A virus in china
Swine Influenza and the 2009 pandemic H1N1

Week 4: Discussion on Ebola Outbreak, and Supplementary Module on Next Generation Informatics for Global Health

Ebola in the wider context
Border controls
Is stopping bushmeat the answer?
How should we use experimental treatments and vaccines?
Should we centralise care and enforce lockdowns?
Will Ebola become airborne?
Will Ebola be become a huge human pandemic like HIV?
Supplementary module: global variation in risk of influenza virus emergence

Week 5: Medical Detective: Bug Hunting in Epidemics

Discovery of a novel microbe: first suspicion
Finding the cause of interstitial pneumonia
The identification of the novel virus associated with this infectious pneumonia
Proof of association & causation: is SARS coronavirus really the cause of SARS?
Control of emerging infections depends on: control at the source
Alert: coronavirus as the cause of emerging infectious diseases!
Supplementary module: using genetic data at multiple scales to understand constraints on viral evolution

Prerequisite

None.

Instructors

Gabriel M. Leung
Professor
The University of Hong Kong

Kwok-Yung Yuen
Professor
The University of Hong Kong

Joseph Wu
Professor
The University of Hong Kong

Mark Jit
Professor
London School of Hygiene & Tropical Medicine

Guan Yi
Professor
The University of Hong Kong

Maria Huachen Zhu
Associate Professor
The University of Hong Kong

Malik Peiris
Professor
The University of Hong Kong

Benjamin Cowling
Professor
The University of Hong Kong

Marc Lipsitch
Professor
Harvard University

Thomas Abraham
Honorary Associate Professor
The University of Hong Kong

Tommy Lam
Assistant Professor
The University of Hong Kong

Platform

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