Emerging and re-emerging viruses
date_range Starts on February 17, 2020
event_note End date April 25, 2020
list 27 sequences
assignment Level : Introductive
chat_bubble_outline Language : English
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Key Information

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verified_user Free certificate
timer 42 hours in total
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Prerequisite

We recommend a good scientific background (such as a bachelor of life science)./ Un bon niveau scientifique est recommandé pour suivre ce MOOC (licence en sciences de la vie).

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Syllabus

Chapter 1 – Introduction/Introduction

  • W1-1: General Introduction / Introduction générale (Albert Osterhaus, Amsterdam)
  • W1-2: Definition: Emerging and re-emerging / Définitions : émergents et ré-emergents (Antoine Gessain, Institut Pasteur)
  • W1-3 : Principles : Vectors, Hosts, Reservoirs… / Principes : vecteurs, hôtes, réservoirs... (Anna-Bella Failloux, Institut Pasteur)
  • W1-4: One Health / Santé globale (Hervé Bourhy, Institut Pasteur)

Chapter 2 – Molecular mechanisms that drive viruses to be emerging or re-emerging /Mécanismes moléculaires qui conduisent à l’émergence ou la ré-émergence d’un virus /

  • W2-1 : Newly identified viruses /Nouveaux virus identifiés (Marc Eloit, Institut Pasteur)
  • W2-2 : Avian Influenza /La grippe aviaire (Jean-Claude Manuguerra, Institut Pasteur)
  • W2-3: Previously known viruses that acquired additional virulence traits: Influenza viruses 1 and 2 / Virus précédemment connus qui ont acquis des caractères de virulence supplémentaires: virus grippaux 1 et 2 (Sylvie van der Werf, Institut Pasteur)
  • W2-4: Control of the host on the virus Contrôle de l'hôte sur le virus (Carla Saleh, Institut Pasteur)

Chapter 3 – Conditions that favor emergence or re-emergence of viruses/Conditions qui favorisent l’émergence ou la ré-émergence d’un virus

  • W3-1: Changes in urbanization, human behavior / Changements dans l'urbanisation, le comportement humain (Pascal Handschumacher UNISTRA)
  • W3-2: Changes in Climate, deforestation, Natural disasters Changements climatiques, déforestation, catastrophes naturelles (Joacim Rocklöv (Université d’Umea, Sweden)
  • W3-3 : Coronavirus : SARS, MERS-CoV Coronavirus : SARS, MERS-CoV (Luis Enjuanes, Madrid)
  • W3-4: Yellow Fever Fièvre jaune (Nolween Jouvenet, Institut Pasteur)
  • W3-5: Hantavirus and Lassa Fever Hantavirus et fièvre de Lassa (Noel Tordo, Institut Pasteur)
  • W3-6: Human-nonhuman primate contact as a driver of viral emergence Le contact humain-non humain avec les primates comme moteur de l'émergence virale (Tamara Gilles-Vernick)
  • W3-7: A 20 year experience of Bluetongue circulation in Europe / Une expérience de 20 ans de la circulation de la fièvre catarrhale du mouton en Europe (Damien Vitour)

Chapter 4 – One health/ Santé globale

  • W4-1: Bornavirus diseases / Maladies à Bornavirus (Hilde Angermeier, Institut Pasteur EUPHEM)
  • W4-2: Nipah Virus / le virus Nipah (Birgit Nikolai)
  • W4-3: Dengue / La Dengue (Marie Flamand, Institut Pasteur)
  • W4-4: Rift valley fever / La fièvre de la vallée du Rift (Benjamin Brennan, Glascow)
  • W4-5: Crimean-Congo virus / Virus Crimée-Congo (Claudia Filippone, Institut Pasteur Madagascar)
  • W4-6: Hepatitis E / L'hépatite E (Nicole Pavio, ANSES Maisons-Alfort)

Chapter 5 : Epidemiology and Modelling / Epidémiologie et modélisations

  • W5-1: Phylogeny and viruses/ Phylogénie et virus (Noël Tordo, Institut Pasteur)
  • W5-2: Epidemiology of Zika / L'épidémiologie de Zika (Arnaud Fontanet, Institut Pasteur)
  • W5-3: Epidemiology of Hepatitis C in Egypt / L'épidémiologie de l'hépatite C en Egypte (Arnaud Fontanet, Institut Pasteur)
  • W5-4: Ebola virus outbreak: From the field to the lab / Épidémie de virus Ebola: du terrain au laboratoire(Christophe Peyrefitte, Institut Pasteur Dakar)
  • W5-5: Quasispecies and viruses / Quasi-Espèces et virus (Esteban Domingo, Madrid)
  • W5-6: Modelling the epidemiology of viral infection / Modélisation de l'épidémiologie de l'infection virale (Simon Cauchemez, Institut Pasteur)

Chapter 6 : Detection, Early management and infection control/Détection, prise en charge et contrôle de l’infection

  • W6-1 : Surveillance of vectors / Surveillance des vecteurs (Norbert Becker, Heidelberg)
  • W6-2 : Surveillance of viral diseases / Surveillance des maladies virales(Harold Noël, Santé Publique France)
  • W6-3 : Molecular epidemiology / Epidémiologie moléculaire (Antoine Gessain, Institut Pasteur)
  • W6-4 : CIBU and Arboviruses / CIBU et Arbovirus (Jessica Vanhomwegen, Institut Pasteur)

Chapter 7 : Prevention and response/Prévention et réponse aux virus émergents

  • EMV W7-1: Vector control activities / Activités de contrôle des vecteurs (Norbert Becker, Heidelberg)
  • W7-2: Bioterrorism lessons from the past and Orthopoxvirus Antiviral strategy approach / Enseignements tirés du bioterrorisme du passé et approche stratégique des antiviraux à orthopoxvirus (Christophe Peyrefitte, Institut Pasteur Dakar)
  • W7-3: Preparedness / Préparation (Marie-Paule Kieny, Inserm)
  • W7-4: Example: OITF of IP / Un exemple : OITF de l'IP(Eileen Farnon/Amber Kunkel/Jean-Claude Manuguerra)
  • W7-5: Public health response: from science to politics / Action de santé publique: de la science à la politique (Didier Houssin, DGS)
  • W7-6: Vaccines / Vaccins (Frédéric Tangy, Institut Pasteur)
  • W7-7: Therapeutics/ Therapeutique (Etienne Decroly, AFMB Polytech, Luminy)
  • W7-8: WHO list of blueprint priority diseases / Liste OMS des maladies prioritaires (Marie-Paule Kieny, WHO)

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Instructors

Jean-Pierre Vartanian
Jean-Pierre Vartanian is Associate Professor at Institut Pasteur (Molecular Retrovirology Unit). He is the co-director of the Fundamental Virology course at the Institut Pasteur. His work is focused on identifying restriction factors involved in viral replication and the role of cellular RNA/DNA editing enzymes with antiviral activity against a range of human pathogens.

Pierre-Emmanuel Ceccaldi
Pierre-Emmanuel Ceccaldi is Professor at Université de Paris and Team Leader in the Epidemiology and Pathophysiology of Oncogenic Viruses Unit, Institut Pasteur. He is the co-director of the Fundamental Virology course at the Institut Pasteur. His work is focused on the interactions of different viruses with host barriers (blood-brain barrier, intestinal barrier…), and neuromuscular system.

Hilde Angermeier
Hilde Angermeier is a microbiologist and post-doctoral fellow within the European Public Health Microbiology training program (EUPHEM) of the European Centre for Disease Prevention and Control (ECDC). She is based for these two years at Institut Pasteur in Paris, France, where she is involved in different surveillance, public health microbiology research, laboratory and outbreak investigation, biorisk and quality management as well as teaching projects. Her ongoing projects involve the characterization of novel Yersinia species, seroprevalence studies on Hantaviruses and Leptospira, the genomic investigation of a recurrent Salmonella outbreak in France as well as the evaluation of the performance of rabies diagnostic tests in the frame of the quality management system present in the National Reference Center (NRC) for rabies. In addition, she has been involved in teaching during a workshop on rabies diagnostic techniques in Zimbabwe and in the development of massive open-online courses (MOOCs) of the Institut Pasteur.

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Institut Pasteur

The Institut Pasteur is a non-profit private French foundation dedicated to the study of biology, microorganisms, diseases and vaccines.

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FUN

France Université Numérique is the broadcaster of the online courses of French higher education institutions and their partners.

It operates several platforms of diffusion, of which the best known, FUN MOOC, is the first French-speaking academic platform worldwide. Thanks to many partner institutions, this platform offers a vast catalog of courses enriched daily with various themes and current events.

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