About the content
If you’re interested in data analysis and interpretation, then this is the data science course for you.
Enhanced throughput: Almost all recently manufactured laptops and desktops include multiple core CPUs. With R, it is very easy to obtain faster turnaround times for analyses by distributing tasks among the cores for concurrent execution. We will discuss how to use Bioconductor to simplify parallel computing for efficient, fault-tolerant, and reproducible high-performance analyses. This will be illustrated with common multicore architectures and Amazon’s EC2 infrastructure.
Enhanced interactivity: New approaches to programming with R and Bioconductor allow researchers to use the web browser as a highly dynamic interface for data interrogation and visualization. We will discuss how to create interactive reports that enable us to move beyond static tables and one-off graphics so that our analysis outputs can be transformed and explored in real time.
Enhanced reproducibility: New methods of virtualization of software environments, exemplified by the Docker ecosystem, are useful for achieving reproducible distributed analyses. The Docker Hub includes a considerable number of container images useful for important Bioconductor-based workflows, and we will illustrate how to use and extend these for sharable and reproducible analysis.
Given the diversity in educational background of our students we have divided the series into seven parts. You can take the entire series or individual courses that interest you. If you are a statistician you should consider skipping the first two or three courses, similarly, if you are biologists you should consider skipping some of the introductory biology lectures. Note that the statistics and programming aspects of the class ramp up in difficulty relatively quickly across the first three courses. By the third course will be teaching advanced statistical concepts such as hierarchical models and by the fourth advanced software engineering skills, such as parallel computing and reproducible research concepts.
The courses in this series will be released sequentially each month and are self-paced:
This class was supported in part by NIH grant R25GM114818.
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- Parallel Computing
- Interactive Graphics
- Reproducible distributed analysis
- Rafael Irizarry
- Vincent Carey
- Michael Love
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Established in 1636 and named for its first benefactor clergyman John Harvard, Harvard is the United States' oldest institution of higher learning, and its history, influence, and wealth have made it one of the world's most prestigious universities. The Harvard Corporation is its first chartered corporation. Although never formally affiliated with any denomination, the early College primarily trained Congregational and Unitarian clergy. Its curriculum and student body were gradually secularized during the 18th century, and by the 19th century, Harvard had emerged as the central cultural establishment among Boston elites. Following the American Civil War, President Charles W. Eliot's long tenure (1869–1909) transformed the college and affiliated professional schools into a modern research university; Harvard was a founding member of the Association of American Universities in 1900. A. Lawrence Lowell, who followed Eliot, further reformed the undergraduate curriculum and undertook aggressive expansion of Harvard's land holdings and physical plant. James Bryant Conant led the university through the Great Depression and World War II and began to reform the curriculum and liberalize admissions after the war. The undergraduate college became coeducational after its 1977 merger with Radcliffe College.
The university is organized into eleven separate academic units—ten faculties and the Radcliffe Institute for Advanced Study—with campuses throughout the Boston metropolitan area: its 209-acre (85 ha) main campus is centered on Harvard Yard in Cambridge, approximately 3 miles (5 km) northwest of Boston; the business school and athletics facilities, including Harvard Stadium, are located across the Charles River in the Allston neighborhood of Boston and the medical, dental, and public health schools are in the Longwood Medical Area. The endowment of Harvard's is worth $37.1 billion, making it the largest of any academic institution.
Harvard is a large, highly residential research university. The nominal cost of attendance is high, but the university's large endowment allows it to offer generous financial aid packages. The Harvard Library is the world's largest academic and private library system, comprising 79 individual libraries holding over 18 million items. The University is cited as one of the world's top tertiary institutions by various organizations.
Harvard's alumni include eight U.S. presidents, several foreign heads of state, 62 living billionaires, 359 Rhodes Scholars, and 242 Marshall Scholars. To date, some 157 Nobel laureates, 18 Fields Medalists, and 14 Turing Award winners have been affiliated as students, faculty, or staff. In addition, Harvard students and alumni have won 10 Academy Awards, 48 Pulitzer Prizes, and 108 Olympic medals (46 gold, 41 silver and 21 bronze).
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