- From fun-mooc.fr
Advanced NMR Spectroscopy
- 6 Sequences
- Intermediate Level
- Starts on October 28, 2024
- Ends on November 11, 2024
Course details
Syllabus
Week 1: Operator description of NMR
Week 2: Relaxation
Week 3: Coherence selection
Week 4: Protein NMR
Week 5: Practical course and NMR metabolomics
Week 6: NMR of glycans and MRI
Prerequisite
This course is intended for undergraduate and graduate students as well as educators and professionals who wish to deepen their understanding of NMR experiments. The participants should have some basic knowledge of NMR spectroscopy and its application for small organic molecules in solution.
Instructors
Olivier Lafon
Dr. Olivier Lafon is a professor at the University of Lille. The focus of his research is to push the frontiers of solid-state NMR spectroscopy in order to gain unique insights into the structure-property relationships of materials used in the fields of bio-economy, energy and health. His current research interests include the development of novel solid-state NMR methods, notably at high magnetic fields, for quadrupolar nuclei or using Dynamic Nuclear Polarization (DNP), as well as their application for the characterization of materials, including heterogeneous catalysts, porous materials and energy materials. Olivier Lafon received a B.Sc. in physical chemistry from the Ecole Normale Supérieure de Lyon. He obtained MS and PhD degrees from the University of Paris South. He was awarded the Magnetic Resonance in Chemistry Award for Young Scientists by the Euromar scientific committee and became a fellow of the Institut Universitaire de France in 2016. He is the chief science officer of the Lille high-field NMR facility, part of the INFRANALYTICS research infrastructure, and the coordinator of the project to install a 1.2 GHz NMR spectrometer in Lille. He is also a member of the editorial board of the journal Solid-State Nuclear Magnetic Resonance.
Patrick Giraudeau
Dr. Patrick Giraudeau is a professor of analytical chemistry at the University of Nantes. His research activities at the CEISAM Research Institute are focused on the development of quantitative NMR methods for the analysis of complex mixtures, including applications to metabolomics and fluxomics. Highlights include the development of fast multidimensional quantitative experiments at high fields and also on benchtop spectrometers as well as recent investigations in dissolution dynamic nuclear polarization. He received his Ph.D. degree in Nantes in 2008, then he worked as a postdoctoral researcher at the Weizmann Institute of Science (Israel). In 2009, he became an Associate Professor at the University of Nantes, where he became a Full Professor in 2017. In 2014, he became a fellow of the Institut Universitaire de France and received a consolidator grant from the European Research Council in 2018. He is an associate editor of Magnetic Resonance in Chemistry, the vice-president of the French Metabolomics and Fluxomics Network (RFMF), and the head of the CEISAM-Corsaire-MetaboHUB NMR facility.
Robert Schneider
Dr. Robert Schneider studied biology and physics in Munich (Germany) and Cambridge (USA). During his Ph.D. thesis at the Max Planck Institute for Biophysical Chemistry in Göttingen (Germany), he applied solid-state NMR spectroscopy to membrane and fibrillar proteins. His work led to a structural model of the inactivated state of a potassium channel as well as of fibrils formed by polyglutamine peptides. As a postdoctoral researcher at the Institut de Biologie Structurale in Grenoble (France), he studied interactions of intrinsically disordered proteins in kinetic detail using solution-state NMR. He has held a position as assistant professor at the University of Lille since 2014, where he continued to study membrane and disordered proteins using NMR spectroscopy in solution and in the solid state. In April 2021, he has taken a position as NMR application scientist with Bruker Biospin in Fällanden (Switzerland).
Luisa Ciobanu
Dr. Luisa Ciobanu is a neurophysicist who focuses on the development of ultra-high field magnetic resonance imaging (UHF-MRI) techniques for the understanding of the fundamental physical principles underlying biological function. Dr. Ciobanu received her doctorate in physics from Ohio State University in 2002. She then went on to do post-doctoral training in the Department of Electrical and Computer Engineering at University of Illinois at Urbana Champaign. After her postdoc, she has held research appointments at the Beckman Institute, University of Illinois at Urbana-Champaign and Pfizer, Inc. (Michigan, Ann Arbor). In 2007, she joined NeuroSpin at CEA-Saclay, France, where she heads the NeuroPhysics team.
Yann Guérardel
Dr. Yann Guérardel is a biochemist whose research focuses on structure-to-function relationships of complex glycoconjugates in different biological contexts including host-parasite interactions and human diseases. He obtained a PhD in biochemistry at Lille University and conducted post-doctoral trainings in Academia Sinica of Taipei (Taiwan) and in Nagoya University (Japan) to develop the use of high-field liquid-state NMR and mass spectrometry for the structural analysis of carbohydrates. He is presently senior researcher at the CNRS, acts as Director of the Institute for Structural and Functional Glycobiology (UGSF, UMR CNRS 8576) and is associate professor at iGCORE, Gifu University, Japan.
Editor
The University of Lille, Science and Technology is a large comprehensive university: science and technology, engineering sciences, social sciences, economic and management sciences. Our university has a strong research potential, varied training offer (over 200 degrees) and a close link with research (35 laboratories).
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